[{"attributes":{"external_reference":"PMID:29367735","risk_allele":"A","p_value":"2.00e-16","beta_coefficient":"0.192 cups per day increase","associated_gene":"HECTD4,MYL2,CUX2,BRAP,ACAD10,ALDH2,MAPKAPK5,NAA25,TRAFD1,RPL6,OAS2,DTX1"},"mapped_to_accession":"EFO:0004330","Variation":"rs2074356","location":"12:112645401-112645401","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"Variation":"rs2074356","mapped_to_accession":"EFO:0004330","attributes":{"odds_ratio":"1.375","risk_allele":"A","external_reference":"PMID:32722627","p_value":"7.00e-8"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"12:112645401-112645401"},{"location":"4:7590819-7590819","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"risk_allele":"A","external_reference":"PMID:31345160","beta_coefficient":"0.123 unit decrease","associated_gene":"SORCS2","p_value":"4.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs11722777"},{"location":"15:75027880-75027880","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31837886","beta_coefficient":"0.136 NR cups per day increase","associated_gene":"CYP1A1","p_value":"2.00e-95"},"Variation":"rs2472297"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:25288136","beta_coefficient":"0.06 unit increase","associated_gene":"ABCG2,PKD2,PPM1K","p_value":"9.00e-8"},"Variation":"rs1481012","location":"4:89039082-89039082","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"2:27730940-27730940","Variation":"rs1260326","attributes":{"p_value":"1.00e-16","associated_gene":"GCKR","beta_coefficient":"0.096 unit increase","external_reference":"PMID:31959922"},"mapped_to_accession":"EFO:0004330"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:75616105-75616105","Variation":"rs17685","attributes":{"p_value":"8.00e-20","associated_gene":"POR","beta_coefficient":"0.059 NR cups per day increase","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"15:75027880-75027880","Variation":"rs2472297","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:25288136","risk_allele":"T","p_value":"2.00e-24","associated_gene":"CYP1A1,CYP1A2","beta_coefficient":"0.14 unit increase"}},{"Variation":"rs62104180","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"5.00e-9","beta_coefficient":"0.0199 unit increase","associated_gene":"FAM150B"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"2:466003-466003"},{"location":"7:17330118-17330118","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31217584","p_value":"6.00e-6","beta_coefficient":"0.01761995 unit increase"},"Variation":"rs62444550"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"HG1257_PATCH:73077005-73077005","Variation":"rs17145750","attributes":{"p_value":"2.00e-10","beta_coefficient":"0.05 NR cups per day increase","associated_gene":"MLXIPL","external_reference":"PMID:31837886","risk_allele":"T"},"mapped_to_accession":"EFO:0004330"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:145062740-145062740","Variation":"rs10227393","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.08 unit decrease","p_value":"9.00e-6","risk_allele":"C","external_reference":"PMID:25288136"}},{"location":"4:88919106-88919106","description":"Caffeine consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"associated_gene":"intergenic","beta_coefficient":"0.065 mg/day decrease","p_value":"5.00e-6","risk_allele":"A","external_reference":"PMID:21490707"},"mapped_to_accession":"EFO:0004330","Variation":"rs2725236"},{"attributes":{"external_reference":"PMID:31959922","p_value":"2.00e-8","beta_coefficient":"0.108 unit increase","associated_gene":"MLXIPL"},"mapped_to_accession":"EFO:0004330","Variation":"rs13234378","location":"7:73026151-73026151","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"location":"HG1257_PATCH:73086484-73086484","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"3.00e-11","beta_coefficient":"0.05 unit decrease","associated_gene":"MLXIPL,TBL2,VPS37D","external_reference":"PMID:25288136","risk_allele":"T"},"Variation":"rs7800944"},{"Variation":"rs10119174","attributes":{"p_value":"1.00e-7","beta_coefficient":"0.0079 unit increase","associated_gene":"LINGO2","external_reference":"PMID:31046077","risk_allele":"G"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"9:27953724-27953724"},{"location":"2:66670976-66670976","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"MEIS1","beta_coefficient":"0.0072 unit increase","p_value":"3.00e-6"},"Variation":"rs1401444"},{"location":"22:41215672-41215672","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.0091 unit increase","associated_gene":"SLC25A17","p_value":"5.00e-8"},"Variation":"rs13054099"},{"mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.02280859 unit increase","p_value":"4.00e-9","external_reference":"PMID:31217584"},"Variation":"rs12670403","location":"7:17309279-17309279","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17285867-17285867","Variation":"rs10281571","attributes":{"p_value":"6.00e-9","beta_coefficient":"0.02623358 unit decrease","external_reference":"PMID:31217584"},"mapped_to_accession":"EFO:0004330"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:27561104","beta_coefficient":"0.081 unit increase","associated_gene":"Intergenic","p_value":"1.00e-8"},"Variation":"rs7745311","location":"6:107565060-107565060","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs34060476","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-23","beta_coefficient":"0.0309338 unit decrease","external_reference":"PMID:32193382","risk_allele":"A"},"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:73037956-73037956"},{"location":"7:17439609-17439609","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"p_value":"1.00e-8","beta_coefficient":"0.053 NR cups per day increase","associated_gene":"KCCAT333","external_reference":"PMID:31837886","risk_allele":"G"},"mapped_to_accession":"EFO:0004330","Variation":"rs6461314"},{"Variation":"rs4877113","mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"UNQ6494","beta_coefficient":"0.0076 unit increase","p_value":"5.00e-7","risk_allele":"G","external_reference":"PMID:31046077"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"9:92245020-92245020"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"9:85229754-85229754","Variation":"rs62579068","attributes":{"associated_gene":"RASEF","beta_coefficient":"0.0094 unit increase","p_value":"6.00e-7","risk_allele":"A","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs71415991","attributes":{"risk_allele":"A","external_reference":"PMID:32193382","beta_coefficient":"0.0253858 unit decrease","p_value":"1.00e-19"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"2:630070-630089"},{"location":"HG1257_PATCH:75450645-75450645","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"1.00e-33","associated_gene":"POR","beta_coefficient":"0.0197 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs1057868"},{"location":"19:41353107-41353107","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"external_reference":"PMID:32193382","risk_allele":"T","p_value":"8.00e-19","beta_coefficient":"0.0186901 unit decrease"},"mapped_to_accession":"EFO:0004330","Variation":"rs56113850"},{"attributes":{"odds_ratio":"1.336","risk_allele":"C","external_reference":"PMID:32722627","p_value":"1.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs2188380","location":"12:111386127-111386127","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"HG1257_PATCH:75517969-75517969","Variation":"rs3779420","attributes":{"associated_gene":"MDH2","beta_coefficient":"0.203 unit decrease","p_value":"2.00e-9","external_reference":"PMID:31959922"},"mapped_to_accession":"EFO:0004330"},{"mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.065 mg/day increase","p_value":"5.00e-6","risk_allele":"A","external_reference":"PMID:21490707"},"Variation":"rs8014204","location":"14:75322794-75322794","source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"14:33819655-33819655","Variation":"rs7159440","attributes":{"p_value":"2.00e-6","associated_gene":"NPAS3","beta_coefficient":"0.0076 unit increase","external_reference":"PMID:31046077","risk_allele":"G"},"mapped_to_accession":"EFO:0004330"},{"location":"15:75019449-75019449","description":"Caffeine consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.12 mg/day increase","associated_gene":"EDC3,CYP1A1,CYP1A2,LMAN1L,CSK","p_value":"5.00e-14","risk_allele":"T","external_reference":"PMID:21490707"},"Variation":"rs2470893"},{"location":"7:17284577-17284577","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"beta_coefficient":"0.1 unit decrease","associated_gene":"AHR","p_value":"3.00e-17","risk_allele":"T","external_reference":"PMID:25288136"},"mapped_to_accession":"EFO:0004330","Variation":"rs4410790"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"2:27730940-27730940","Variation":"rs1260326","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:25288136","risk_allele":"T","p_value":"7.00e-8","associated_gene":"GCKR,FNDC4","beta_coefficient":"0.04 unit decrease"}},{"Variation":"rs11766104","attributes":{"risk_allele":"T","external_reference":"PMID:31837886","beta_coefficient":"0.043 NR cups per day increase","associated_gene":"AHR","p_value":"5.00e-8"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17192272-17192272"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"3:50531201-50531201","Variation":"rs6792502","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"2.00e-6","associated_gene":"CACNA2D2","beta_coefficient":"0.01 unit increase"},"mapped_to_accession":"EFO:0004330"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:32193382","risk_allele":"C","p_value":"1.00e-182","beta_coefficient":"0.0685684 unit decrease"},"Variation":"rs2472297","location":"15:75027880-75027880","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"HSCHR6_MHC_MCF:31952192-31952192","Variation":"rs586346","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"7.00e-10","associated_gene":"C2","beta_coefficient":"0.0095 unit increase"}},{"Variation":"rs17685","attributes":{"external_reference":"PMID:31837886","risk_allele":"A","p_value":"8.00e-20","associated_gene":"POR","beta_coefficient":"0.059 NR cups per day increase"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HG1257_PATCH:75451744-75451744"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"19:47569003-47569003","Variation":"rs3810291","attributes":{"beta_coefficient":"0.013878 unit decrease","p_value":"4.00e-10","risk_allele":"G","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs597045","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"6.00e-11","associated_gene":"OR8U8","beta_coefficient":"0.0106 unit increase"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"11:56272114-56272114"},{"attributes":{"risk_allele":"C","external_reference":"PMID:31046077","beta_coefficient":"0.0136 unit increase","associated_gene":"GCKR","p_value":"1.00e-19"},"mapped_to_accession":"EFO:0004330","Variation":"rs1260326","location":"2:27730940-27730940","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"location":"19:47569003-47569003","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"ZC3H4","beta_coefficient":"0.0092 unit increase","p_value":"7.00e-9"},"Variation":"rs3810291"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:69466359-69466359","Variation":"rs149693390","attributes":{"p_value":"3.00e-6","beta_coefficient":"0.0336 unit increase","associated_gene":"CPM","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330"},{"attributes":{"p_value":"2.00e-25","beta_coefficient":"0.023 unit increase","associated_gene":"LOC101927630","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","Variation":"rs73073176","location":"7:17562952-17562952","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31837886","beta_coefficient":"0.048 NR cups per day increase","associated_gene":"HLA-DQA2","p_value":"6.00e-9"},"Variation":"rs9275576","location":"HSCHR6_MHC_DBB:32657833-32657833","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs2106727","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31217584","p_value":"2.00e-11","beta_coefficient":"0.02594639 unit increase"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17287998-17287998"},{"Variation":"rs2470893","attributes":{"risk_allele":"T","external_reference":"PMID:25288136","beta_coefficient":"0.2 unit increase","associated_gene":"CYP1A1,CYP1A2","p_value":"5.00e-19"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"15:75019449-75019449"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"1:40049184-40049184","Variation":"rs11206378","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","beta_coefficient":"0.0078 unit increase","associated_gene":"PABPC4","p_value":"4.00e-7"},"mapped_to_accession":"EFO:0004330"},{"location":"11:132616073-132616073","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"3.00e-7","beta_coefficient":"0.0079 unit increase","associated_gene":"OPCML","external_reference":"PMID:31046077","risk_allele":"G"},"Variation":"rs3016390"},{"location":"15:75320433-75320433","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.044 NR cups per day decrease","associated_gene":"PPCDC","p_value":"1.00e-10","risk_allele":"T","external_reference":"PMID:31837886"},"Variation":"rs8042558"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"HG1257_PATCH:75451744-75451744","Variation":"rs17685","attributes":{"p_value":"4.00e-11","beta_coefficient":"0.07 unit increase","associated_gene":"POR,SNORA14A,TMEM120A","external_reference":"PMID:25288136","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"location":"7:17284577-17284577","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31217584","p_value":"6.00e-16","beta_coefficient":"0.03071323 unit increase"},"Variation":"rs4410790"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31959922","p_value":"5.00e-17","associated_gene":"LOC102659288","beta_coefficient":"0.109 unit decrease"},"Variation":"rs10259316","location":"7:17445706-17445706","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"15:76089052-76089052","Variation":"rs112252316","attributes":{"beta_coefficient":"0.0382196 unit decrease","p_value":"1.00e-16","risk_allele":"C","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"2:146316319-146316319","Variation":"rs10193706","attributes":{"p_value":"1.00e-6","associated_gene":"TEX41","beta_coefficient":"0.0072 unit increase","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330"},{"location":"HG1257_PATCH:75451744-75451744","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"beta_coefficient":"0.08 unit increase","associated_gene":"POR,SNORA14A,TMEM120A","p_value":"1.00e-9","risk_allele":"A","external_reference":"PMID:25288136"},"mapped_to_accession":"EFO:0004330","Variation":"rs17685"},{"Variation":"rs7580688","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","associated_gene":"SFT2D3","beta_coefficient":"0.0073 unit increase","p_value":"9.00e-6"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"2:128457941-128457941"},{"mapped_to_accession":"EFO:0004330","attributes":{"p_value":"9.00e-8","beta_coefficient":"0.076 unit increase","associated_gene":"CYP2G1P,CYP2A7P2","external_reference":"PMID:31959922"},"Variation":"rs72480748","location":"19:41414481-41414481","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs6495122","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"7.00e-9","associated_gene":"CPLX3,ULK3","beta_coefficient":"0.05 unit decrease","external_reference":"PMID:21876539","risk_allele":"A"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"15:75125645-75125645"},{"mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"LINC01378","beta_coefficient":"0.0071 unit increase","p_value":"3.00e-6","risk_allele":"C","external_reference":"PMID:31046077"},"Variation":"rs7664424","location":"4:118342375-118342375","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-21","associated_gene":"FTO","beta_coefficient":"0.0142 unit increase","external_reference":"PMID:31046077","risk_allele":"A"},"Variation":"rs9937053","location":"16:53799507-53799507","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"Variation":"rs4077582","attributes":{"p_value":"8.00e-15","associated_gene":"CYP11A1","beta_coefficient":"0.05 NR cups per day increase","external_reference":"PMID:31837886","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"15:74665622-74665622"},{"Variation":"rs79105258","attributes":{"odds_ratio":"1.338","risk_allele":"A","external_reference":"PMID:32722627","p_value":"4.00e-7"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"12:111718231-111718231"},{"Variation":"rs6265","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31959922","p_value":"3.00e-6","beta_coefficient":"0.054 unit decrease","associated_gene":"BDNF"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"11:27679916-27679916"},{"location":"6:32679326-32679326","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"external_reference":"PMID:31837886","risk_allele":"T","p_value":"6.00e-9","associated_gene":"HLA-DQA2","beta_coefficient":"0.048 NR cups per day increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs9275576"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"18:40841185-40841185","Variation":"rs4624274","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"1.00e-6","beta_coefficient":"0.0073 unit increase","associated_gene":"SYT4"}},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17519261-17519261","Variation":"rs6949509","attributes":{"risk_allele":"G","external_reference":"PMID:31837886","beta_coefficient":"0.042 NR cups per day decrease","associated_gene":"LOC101927630","p_value":"2.00e-12"},"mapped_to_accession":"EFO:0004330"},{"attributes":{"beta_coefficient":"0.0088 unit increase","associated_gene":"EYA2","p_value":"9.00e-9","risk_allele":"T","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","Variation":"rs6124969","location":"20:45816277-45816277","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"location":"11:42548520-42548520","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.0119 unit increase","associated_gene":"LOC100507205","p_value":"2.00e-6"},"Variation":"rs58867452"},{"Variation":"rs4245116","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:25288136","risk_allele":"T","p_value":"2.00e-6","beta_coefficient":"0.03 unit increase"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"11:133256561-133256561"},{"attributes":{"external_reference":"PMID:21876539","risk_allele":"A","p_value":"8.00e-7","associated_gene":"NCALD","beta_coefficient":"0.056 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs16868941","location":"8:103052377-103052377","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"Variation":"rs4475789","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"1.00e-7","associated_gene":"OR2M2","beta_coefficient":"0.0083 unit increase"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"1:248352334-248352334"},{"location":"7:17396747-17396752","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.02023615 unit increase","p_value":"1.00e-7","external_reference":"PMID:31217584"},"Variation":"rs10683220"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"9:23713214-23713214","Variation":"rs3829087","attributes":{"beta_coefficient":"0.0142189 unit decrease","p_value":"5.00e-8","risk_allele":"G","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs34060476","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"2.00e-18","beta_coefficient":"0.019 unit increase","associated_gene":"MLXIPL"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:73037956-73037956"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:89662674-89662674","Variation":"rs17687539","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"4.00e-8","beta_coefficient":"0.01 unit increase","associated_gene":"STEAP2-AS1"}},{"attributes":{"beta_coefficient":"0.203 unit decrease","associated_gene":"MDH2","p_value":"2.00e-9","external_reference":"PMID:31959922"},"mapped_to_accession":"EFO:0004330","Variation":"rs3779420","location":"7:75682330-75682330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"7.00e-10","beta_coefficient":"0.0095 unit increase","associated_gene":"C2"},"mapped_to_accession":"EFO:0004330","Variation":"rs586346","location":"HSCHR6_MHC_QBL:31866104-31866104","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"19:41353107-41353107","Variation":"rs56113850","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"8.00e-16","beta_coefficient":"0.0121 unit increase","associated_gene":"CYP2A6"}},{"location":"11:56267330-56267330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"external_reference":"PMID:32193382","risk_allele":"T","p_value":"1.00e-8","beta_coefficient":"0.0127637 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs643017"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"8.00e-7","associated_gene":"EIF3E","beta_coefficient":"0.0086 unit increase"},"Variation":"rs395815","location":"8:109156532-109156532","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs10275488","attributes":{"external_reference":"PMID:31217584","p_value":"1.00e-9","beta_coefficient":"0.02801235 unit decrease"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17303778-17303778"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"18:57852587-57852587","Variation":"rs476828","attributes":{"associated_gene":"MC4R","beta_coefficient":"0.043 NR cups per day increase","p_value":"2.00e-10","risk_allele":"C","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330"},{"source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption","location":"15:75382542-75382542","Variation":"rs12148488","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.07 mg/day decrease","associated_gene":"SCAMP5,PPCDC","p_value":"6.00e-7","risk_allele":"T","external_reference":"PMID:21490707"}},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"JADE2","beta_coefficient":"0.007 unit increase","p_value":"3.00e-6"},"Variation":"rs329124","location":"5:133865452-133865452","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"attributes":{"associated_gene":"MIR2113","beta_coefficient":"0.067 unit increase","p_value":"3.00e-8","external_reference":"PMID:31959922"},"mapped_to_accession":"EFO:0004330","Variation":"rs12189679","location":"6:98333409-98333409","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"12:112511913-112511913","Variation":"rs116873087","attributes":{"external_reference":"PMID:32722627","odds_ratio":"1.343","risk_allele":"C","p_value":"2.00e-7"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs382140","mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"LAMB4,NRCAM","beta_coefficient":"0.079 unit increase","p_value":"4.00e-9","risk_allele":"A","external_reference":"PMID:21876539"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:107782200-107782200"},{"location":"6:107555018-107555018","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:27561104","associated_gene":"Intergenic","beta_coefficient":"0.082 unit increase","p_value":"1.00e-8"},"Variation":"rs6942255"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"6:98560826-98560826","Variation":"rs1906251","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.0073 unit increase","associated_gene":"MIR2113","p_value":"2.00e-6","risk_allele":"A","external_reference":"PMID:31046077"}},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"12:112627350-112627350","Variation":"rs144504271","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-15","associated_gene":"HECTD4","beta_coefficient":"0.1887 cups per day increase","external_reference":"PMID:29367735","risk_allele":"A"}},{"location":"15:74558078-74558078","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"7.00e-13","associated_gene":"CCDC33","beta_coefficient":"0.052 NR cups per day decrease","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330","Variation":"rs4886593"},{"Variation":"rs10802317","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","associated_gene":"SMYD3","beta_coefficient":"0.0068 unit increase","p_value":"9.00e-6"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"1:246167009-246167009"},{"Variation":"rs1153598","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"2.00e-6","associated_gene":"RARB","beta_coefficient":"0.0103 unit increase"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"3:25569043-25569043"},{"Variation":"rs1057868","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.0197 unit increase","associated_gene":"POR","p_value":"1.00e-33"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:75615006-75615006"},{"location":"17:17711270-17711270","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"risk_allele":"A","external_reference":"PMID:32193382","beta_coefficient":"0.0141622 unit decrease","p_value":"2.00e-10"},"mapped_to_accession":"EFO:0004330","Variation":"rs4925114"},{"location":"16:88771054-88771054","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.0212 unit increase","associated_gene":"RNF166","p_value":"2.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs116094457"},{"location":"7:73026378-73026378","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"associated_gene":"MLXIPL","beta_coefficient":"0.05 NR cups per day increase","p_value":"2.00e-10","risk_allele":"T","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330","Variation":"rs17145750"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"5:87950543-87950543","Variation":"rs16903275","attributes":{"associated_gene":"LINC00461","beta_coefficient":"0.0138 unit increase","p_value":"7.00e-12","risk_allele":"A","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs12231737","attributes":{"odds_ratio":"1.318","risk_allele":"T","external_reference":"PMID:32722627","p_value":"5.00e-7"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:112574616-112574616"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"5:163927085-163927085","Variation":"rs874573","attributes":{"p_value":"3.00e-8","beta_coefficient":"0.0136508 unit decrease","external_reference":"PMID:32193382","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"location":"7:75611756-75611756","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31959922","beta_coefficient":"0.067 unit increase","associated_gene":"POR","p_value":"1.00e-8"},"Variation":"rs3815455"},{"Variation":"rs7791070","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31837886","associated_gene":"AHR","beta_coefficient":"0.076 NR cups per day decrease","p_value":"2.00e-28"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17401027-17401027"},{"Variation":"rs2465037","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","associated_gene":"PKHD1","beta_coefficient":"0.0103 unit increase","p_value":"4.00e-11"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"6:51179260-51179260"},{"Variation":"rs3815455","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"1.00e-8","beta_coefficient":"0.067 unit increase","associated_gene":"POR","external_reference":"PMID:31959922"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"HG1257_PATCH:75447395-75447395"},{"Variation":"rs660550","attributes":{"risk_allele":"A","external_reference":"PMID:31837886","beta_coefficient":"0.034 NR cups per day decrease","associated_gene":"SLC44A4","p_value":"8.00e-9"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_MCF:31913754-31913754"},{"Variation":"rs2613458","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","beta_coefficient":"0.0093 unit increase","associated_gene":"CADM1","p_value":"1.00e-8"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"11:115474581-115474581"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17287269-17287269","Variation":"rs6968865","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31217584","beta_coefficient":"0.02987925 unit increase","p_value":"4.00e-15"}},{"location":"7:17277692-17277692","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","beta_coefficient":"0.0421 unit increase","associated_gene":"AHR","p_value":"4.00e-10"},"mapped_to_accession":"EFO:0004330","Variation":"rs117692895"},{"attributes":{"associated_gene":"ADD1","beta_coefficient":"0.04 NR cups per day decrease","p_value":"3.00e-10","risk_allele":"T","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330","Variation":"rs1877723","location":"4:2846799-2846799","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"attributes":{"p_value":"5.00e-36","beta_coefficient":"0.0290606 unit decrease","external_reference":"PMID:32193382","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","Variation":"rs1057868","location":"HG1257_PATCH:75450645-75450645","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"location":"2:32762481-32762481","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","beta_coefficient":"0.014 unit increase","associated_gene":"BIRC6","p_value":"9.00e-7"},"Variation":"rs111994577"},{"mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.073 NR cups per day decrease","associated_gene":"KCCAT333","p_value":"3.00e-11","risk_allele":"A","external_reference":"PMID:31837886"},"Variation":"rs17645813","location":"7:17419697-17419697","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17551902-17551902","Variation":"rs17706320","attributes":{"risk_allele":"C","external_reference":"PMID:31837886","associated_gene":"LOC101927630","beta_coefficient":"0.05 NR cups per day decrease","p_value":"5.00e-16"},"mapped_to_accession":"EFO:0004330"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"HG1257_PATCH:73076778-73076778","Variation":"rs13234378","mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"MLXIPL","beta_coefficient":"0.108 unit increase","p_value":"2.00e-8","external_reference":"PMID:31959922"}},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"HSCHR6_MHC_QBL:31827669-31827669","Variation":"rs660550","attributes":{"p_value":"8.00e-9","beta_coefficient":"0.034 NR cups per day decrease","associated_gene":"SLC44A4","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"location":"HSCHR6_MHC_QBL:32607998-32607998","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"associated_gene":"HLA-DQA2","beta_coefficient":"0.048 NR cups per day increase","p_value":"6.00e-9","risk_allele":"T","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330","Variation":"rs9275576"},{"location":"17:17715317-17715317","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"associated_gene":"SREBF1","beta_coefficient":"0.0092 unit increase","p_value":"3.00e-9","risk_allele":"G","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","Variation":"rs2297508"},{"Variation":"rs7502307","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-8","beta_coefficient":"0.0148724 unit decrease","external_reference":"PMID:32193382","risk_allele":"C"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"17:65989961-65989961"},{"location":"14:33075243-33075243","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"2.00e-8","associated_gene":"AKAP6","beta_coefficient":"0.0084 unit increase","external_reference":"PMID:31046077","risk_allele":"G"},"mapped_to_accession":"EFO:0004330","Variation":"rs1956218"},{"source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption","location":"7:72856269-72856269","Variation":"rs2240466","attributes":{"external_reference":"PMID:21490707","risk_allele":"A","p_value":"1.00e-6","beta_coefficient":"0.1109 mg/day increase"},"mapped_to_accession":"EFO:0004330"},{"attributes":{"p_value":"2.00e-8","beta_coefficient":"0.04 NR cups per day increase","associated_gene":"DENND1B","external_reference":"PMID:31837886","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","Variation":"rs2488397","location":"1:197701279-197701279","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:31837886","beta_coefficient":"0.034 NR cups per day decrease","associated_gene":"SLC44A4","p_value":"8.00e-9"},"Variation":"rs660550","location":"HSCHR6_MHC_SSTO:31829163-31829163","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"Variation":"rs1349140","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31959922","associated_gene":"LOC101927630","beta_coefficient":"0.155 unit increase","p_value":"2.00e-18"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:17562859-17562859"},{"location":"15:75329091-75329091","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"risk_allele":"C","external_reference":"PMID:31837886","associated_gene":"PPCDC","beta_coefficient":"0.053 NR cups per day increase","p_value":"2.00e-17"},"mapped_to_accession":"EFO:0004330","Variation":"rs12917120"},{"location":"1:150586971-150586971","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.078 unit decrease","associated_gene":"ENSA,MCL1","p_value":"1.00e-10","external_reference":"PMID:31959922"},"Variation":"rs6681426"},{"Variation":"rs34772466","attributes":{"risk_allele":"A","external_reference":"PMID:32193382","beta_coefficient":"0.0154144 unit decrease","p_value":"1.00e-12"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"20:45824588-45824588"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:11189966-11189966","Variation":"rs2597979","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","associated_gene":"PRH1-PRR4","beta_coefficient":"0.0111 unit increase","p_value":"3.00e-9"}},{"location":"22:24878218-24878218","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"external_reference":"PMID:31959922","p_value":"4.00e-10","associated_gene":"ADORA2A-AS1","beta_coefficient":"0.073 unit decrease"},"mapped_to_accession":"EFO:0004330","Variation":"rs5760444"},{"location":"6:107551281-107551281","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"9.00e-9","associated_gene":"Intergenic","beta_coefficient":"0.082 unit increase","external_reference":"PMID:27561104"},"Variation":"rs7754744"},{"location":"12:48842645-48842645","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"6.00e-6","beta_coefficient":"0.0199 unit increase","associated_gene":"ANP32D"},"Variation":"rs73102648"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"1:177873210-177873210","Variation":"rs574367","attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"5.00e-10","beta_coefficient":"0.0112 unit increase","associated_gene":"SEC16B"},"mapped_to_accession":"EFO:0004330"},{"location":"12:112230019-112230019","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"risk_allele":"C","odds_ratio":"1.322","external_reference":"PMID:32722627","p_value":"5.00e-7"},"mapped_to_accession":"EFO:0004330","Variation":"rs4646776"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"6:65482440-65482440","Variation":"rs7774229","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","beta_coefficient":"0.0127 unit increase","associated_gene":"EYS","p_value":"7.00e-6"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs117810762","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"CYP2E1","beta_coefficient":"0.0298 unit increase","p_value":"1.00e-7"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"10:135315795-135315795"},{"location":"1:177861357-177861357","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"risk_allele":"G","external_reference":"PMID:32193382","beta_coefficient":"0.0159559 unit decrease","p_value":"3.00e-10"},"mapped_to_accession":"EFO:0004330","Variation":"rs661691"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:17334899-17334899","Variation":"rs4719497","attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"2.00e-8","associated_gene":"AHR","beta_coefficient":"0.0121 unit increase"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs12699844","attributes":{"p_value":"2.00e-16","beta_coefficient":"0.0122 unit increase","associated_gene":"KCCAT333","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:17443199-17443199"},{"Variation":"rs2472297","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","associated_gene":"CYP1A1","beta_coefficient":"0.0447 unit increase","p_value":"9.00e-157"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"15:75027880-75027880"},{"Variation":"rs11066280","attributes":{"p_value":"6.00e-6","external_reference":"PMID:32722627","risk_allele":"A","odds_ratio":"1.283"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:112817783-112817783"},{"mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.0122471 unit increase","p_value":"2.00e-8","risk_allele":"A","external_reference":"PMID:32193382"},"Variation":"rs2844232","location":"8:110570060-110570060","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31837886","risk_allele":"A","p_value":"1.00e-19","beta_coefficient":"0.062 NR cups per day decrease","associated_gene":"STRA6"},"Variation":"rs351242","location":"15:74472716-74472716","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"1.00e-6","associated_gene":"LOC100996635","beta_coefficient":"0.0104 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs6593661","location":"1:95989137-95989137","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.01 unit increase","associated_gene":"PCMTD2","p_value":"2.00e-11"},"Variation":"rs6062682","location":"20:62891820-62891820","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs4410790","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:32193382","risk_allele":"T","p_value":"1.00e-150","beta_coefficient":"0.0568791 unit decrease"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17284577-17284577"},{"location":"12:112241766-112241766","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"external_reference":"PMID:31959922","p_value":"4.00e-153","associated_gene":"ALDH2","beta_coefficient":"0.354 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs671"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"HSCHR12_2_CTG2:11189966-11189966","Variation":"rs2597979","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","beta_coefficient":"0.0111 unit increase","associated_gene":"PRH1-PRR4","p_value":"3.00e-9"},"mapped_to_accession":"EFO:0004330"},{"location":"16:70927078-70927078","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"4.00e-8","beta_coefficient":"0.0087 unit increase","associated_gene":"HYDIN","external_reference":"PMID:31046077","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","Variation":"rs8056750"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:29367735","associated_gene":"AGR3,AHR","beta_coefficient":"0.102 cups per day increase","p_value":"5.00e-7"},"Variation":"rs4410790","location":"7:17284577-17284577","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17324624-17324624","Variation":"rs2892838","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.01760686 unit increase","p_value":"9.00e-6","external_reference":"PMID:31217584"}},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"6:31875712-31875712","Variation":"rs586346","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","beta_coefficient":"0.0095 unit increase","associated_gene":"C2","p_value":"7.00e-10"}},{"Variation":"rs660550","attributes":{"p_value":"8.00e-9","beta_coefficient":"0.034 NR cups per day decrease","associated_gene":"SLC44A4","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_DBB:31819462-31819462"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31837886","associated_gene":"HLA-DQA2","beta_coefficient":"0.048 NR cups per day increase","p_value":"6.00e-9"},"Variation":"rs9275576","location":"HSCHR6_MHC_SSTO:32770107-32770107","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"attributes":{"risk_allele":"C","external_reference":"PMID:31046077","associated_gene":"SND1","beta_coefficient":"0.0199 unit increase","p_value":"7.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs181624422","location":"7:127406716-127406716","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"location":"11:60863141-60863141","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"T","p_value":"1.00e-7","beta_coefficient":"0.022 unit increase","associated_gene":"CD5"},"Variation":"rs11518562"},{"description":"Caffeine consumption","source":"NHGRI-EBI GWAS catalog","location":"15:75044238-75044238","Variation":"rs2472304","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"A","external_reference":"PMID:21490707","beta_coefficient":"0.08 mg/day increase","associated_gene":"CYP1A2","p_value":"3.00e-7"}},{"location":"17:46150145-46150155","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"beta_coefficient":"0.015647 unit increase","p_value":"2.00e-10","risk_allele":"C","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330","Variation":"rs35841265"},{"location":"1:177334782-177334782","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"2.00e-7","associated_gene":"LOC102724661","beta_coefficient":"0.0132 unit increase"},"Variation":"rs4233170"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"11:36868287-36868287","Variation":"rs2422370","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"6.00e-7","associated_gene":"C11orf74","beta_coefficient":"0.0104 unit increase","external_reference":"PMID:31046077","risk_allele":"A"}},{"location":"HG1133_PATCH:11190269-11190269","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"3.00e-9","associated_gene":"PRH1-PRR4","beta_coefficient":"0.0111 unit increase","external_reference":"PMID:31046077","risk_allele":"G"},"mapped_to_accession":"EFO:0004330","Variation":"rs2597979"},{"location":"7:17284577-17284577","source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption","attributes":{"p_value":"2.00e-19","associated_gene":"AHR","beta_coefficient":"0.15 mg/day decrease","external_reference":"PMID:21490707","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","Variation":"rs4410790"},{"Variation":"rs573194563","attributes":{"associated_gene":"CT49,DNAH5","beta_coefficient":"0.2708 cups per day increase","p_value":"5.00e-7","risk_allele":"CA","external_reference":"PMID:29367735"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"5:13076921-13076924"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"15:74133413-74133413","Variation":"rs11855112","attributes":{"p_value":"3.00e-8","associated_gene":"TBC1D21","beta_coefficient":"0.049 NR cups per day increase","external_reference":"PMID:31837886","risk_allele":"C"},"mapped_to_accession":"EFO:0004330"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"4:89045331-89045331","Variation":"rs2199936","attributes":{"beta_coefficient":"0.0153 unit increase","associated_gene":"ABCG2","p_value":"4.00e-11","risk_allele":"G","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs10992783","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","beta_coefficient":"0.0071 unit increase","associated_gene":"FAM120A","p_value":"2.00e-6"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"9:96311256-96311256"},{"location":"HSCHR6_MHC_MANN:32833069-32833069","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.048 NR cups per day increase","associated_gene":"HLA-DQA2","p_value":"6.00e-9","risk_allele":"T","external_reference":"PMID:31837886"},"Variation":"rs9275576"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"HSCHR6_MHC_COX:31863263-31863263","Variation":"rs586346","mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"C2","beta_coefficient":"0.0095 unit increase","p_value":"7.00e-10","risk_allele":"T","external_reference":"PMID:31046077"}},{"Variation":"rs1481012","mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"ABCG2","beta_coefficient":"0.066 NR cups per day decrease","p_value":"2.00e-12","risk_allele":"G","external_reference":"PMID:31837886"},"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"4:89039082-89039082"},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","associated_gene":"CCDC36","beta_coefficient":"0.0072 unit increase","p_value":"2.00e-6"},"Variation":"rs13064780","location":"3:49274826-49274826","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"location":"1:116891363-116891363","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"associated_gene":"MAB21L3,ATP1A1","beta_coefficient":"0.2139 cups per day increase","p_value":"8.00e-7","risk_allele":"G","external_reference":"PMID:29367735"},"mapped_to_accession":"EFO:0004330","Variation":"rs12094032"},{"location":"1:150930926-150930926","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","associated_gene":"SETDB1","beta_coefficient":"0.0185 unit increase","p_value":"9.00e-6"},"Variation":"rs114908993"},{"Variation":"rs57918684","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.0129 unit increase","associated_gene":"MED13","p_value":"2.00e-10","risk_allele":"A","external_reference":"PMID:31046077"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"17:60150383-60150383"},{"location":"1:44022303-44022303","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"4.00e-6","associated_gene":"PTPRF","beta_coefficient":"0.0082 unit increase","external_reference":"PMID:31046077","risk_allele":"A"},"Variation":"rs2494995"},{"Variation":"rs7947502","attributes":{"associated_gene":"NCAM1","beta_coefficient":"0.0075 unit increase","p_value":"6.00e-7","risk_allele":"C","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"HG306_PATCH:112909396-112909396"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"7:17284577-17284577","Variation":"rs4410790","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"6.00e-70","beta_coefficient":"0.108 NR cups per day increase","associated_gene":"AHR","external_reference":"PMID:31837886","risk_allele":"C"}},{"mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:21876539","beta_coefficient":"0.0675 unit increase","associated_gene":"CYP1A1,CYP1A2","p_value":"2.00e-11"},"Variation":"rs2470893","location":"15:75019449-75019449","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"2:27730940-27730940","Variation":"rs1260326","attributes":{"associated_gene":"GCKR","beta_coefficient":"0.033 NR cups per day increase","p_value":"2.00e-8","risk_allele":"C","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330"},{"mapped_to_accession":"EFO:0004330","attributes":{"p_value":"8.00e-19","associated_gene":"MC4R","beta_coefficient":"0.0155 unit increase","external_reference":"PMID:31046077","risk_allele":"A"},"Variation":"rs66723169","location":"18:57808978-57808978","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"attributes":{"external_reference":"PMID:31217584","beta_coefficient":"0.02918148 unit decrease","p_value":"4.00e-10"},"mapped_to_accession":"EFO:0004330","Variation":"rs10252701","location":"7:17280513-17280513","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_COX:31824827-31824827","Variation":"rs660550","attributes":{"external_reference":"PMID:31837886","risk_allele":"A","p_value":"8.00e-9","associated_gene":"SLC44A4","beta_coefficient":"0.034 NR cups per day decrease"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs77936935","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"5.00e-6","beta_coefficient":"0.0199 unit increase","associated_gene":"BRINP1"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"9:122039564-122039564"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"8:40399074-40399074","Variation":"rs144885044","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"C","external_reference":"PMID:31046077","associated_gene":"ZMAT4","beta_coefficient":"0.0286 unit increase","p_value":"4.00e-6"}},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:25288136","risk_allele":"A","p_value":"3.00e-8","associated_gene":"EFCAB5,SSH2,CCDC55","beta_coefficient":"0.03 unit decrease"},"Variation":"rs9902453","location":"17:28349095-28349095","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"location":"15:75125645-75125645","description":"Caffeine consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"6.00e-7","beta_coefficient":"0.07 mg/day decrease","associated_gene":"CYP1A2,LMAN1L,SCAMP2,CPLX3,MP1,CSK,ULK3,COX5A,C14orf17","external_reference":"PMID:21490707","risk_allele":"A"},"mapped_to_accession":"EFO:0004330","Variation":"rs6495122"},{"location":"7:17385507-17385509","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"1.00e-6","beta_coefficient":"0.01887579 unit increase","external_reference":"PMID:31217584"},"Variation":"rs11400459"},{"description":"Caffeine consumption","source":"NHGRI-EBI GWAS catalog","location":"5:104867936-104867936","Variation":"rs7447447","attributes":{"p_value":"7.00e-6","beta_coefficient":"0.1521 mg/day increase","external_reference":"PMID:21490707","risk_allele":"T"},"mapped_to_accession":"EFO:0004330"},{"location":"5:53344352-53344352","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"3.00e-7","associated_gene":"ARL15","beta_coefficient":"0.0094 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs58203904"},{"Variation":"rs9398171","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-8","beta_coefficient":"0.0128985 unit decrease","external_reference":"PMID:32193382","risk_allele":"C"},"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"6:108983527-108983527"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"22:24874523-24874523","Variation":"rs62234058","attributes":{"p_value":"1.00e-12","associated_gene":"ADORA2A","beta_coefficient":"0.047 unit decrease","external_reference":"PMID:31217584"},"mapped_to_accession":"EFO:0004330"},{"attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"3.00e-6","associated_gene":"RAB30-AS1","beta_coefficient":"0.0087 unit increase"},"mapped_to_accession":"EFO:0004330","Variation":"rs17144566","location":"11:82798226-82798226","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption","location":"HG1257_PATCH:72906896-72906896","Variation":"rs2240466","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:21490707","risk_allele":"A","p_value":"1.00e-6","beta_coefficient":"0.1109 mg/day increase"}},{"location":"8:109114426-109114426","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","attributes":{"beta_coefficient":"0.0144948 unit increase","p_value":"1.00e-9","risk_allele":"C","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330","Variation":"rs13271359"},{"attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"GRID2","beta_coefficient":"0.007 unit increase","p_value":"3.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs1503212","location":"4:94075844-94075844","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"4:159802267-159802267","Variation":"rs35189787","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"T","external_reference":"PMID:31046077","associated_gene":"FNIP2","beta_coefficient":"0.0089 unit increase","p_value":"2.00e-6"}},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:17593486-17593486","Variation":"rs13233604","attributes":{"p_value":"5.00e-12","beta_coefficient":"0.058 NR cups per day decrease","associated_gene":"LOC101927630","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"HG747_PATCH:65989961-65989961","Variation":"rs7502307","attributes":{"p_value":"2.00e-8","beta_coefficient":"0.0148724 unit decrease","external_reference":"PMID:32193382","risk_allele":"C"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs660550","attributes":{"p_value":"8.00e-9","associated_gene":"SLC44A4","beta_coefficient":"0.034 NR cups per day decrease","external_reference":"PMID:31837886","risk_allele":"A"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_APD:31848635-31848635"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_COX:32602737-32602737","Variation":"rs9275576","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.048 NR cups per day increase","associated_gene":"HLA-DQA2","p_value":"6.00e-9","risk_allele":"T","external_reference":"PMID:31837886"}},{"location":"16:89851033-89851033","source":"NHGRI-EBI GWAS catalog","description":"Caffeine consumption","attributes":{"beta_coefficient":"0.118 mg/day increase","p_value":"6.00e-6","risk_allele":"T","external_reference":"PMID:21490707"},"mapped_to_accession":"EFO:0004330","Variation":"rs16966142"},{"Variation":"rs10865548","attributes":{"beta_coefficient":"0.016 unit increase","associated_gene":"TMEM18","p_value":"2.00e-16","risk_allele":"G","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"2:631606-631606"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"5:125189255-125189255","Variation":"rs1432343","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"5.00e-8","associated_gene":"ABCG2","beta_coefficient":"0.069 unit increase","external_reference":"PMID:31959922"}},{"location":"3:134157263-134157263","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"2.00e-7","associated_gene":"MIR4788","beta_coefficient":"0.0079 unit increase","external_reference":"PMID:31046077","risk_allele":"A"},"Variation":"rs13088645"},{"Variation":"rs79105258","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31345160","risk_allele":"A","p_value":"1.00e-14","associated_gene":"CUX2","beta_coefficient":"0.173 unit increase"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:111718231-111718231"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"19:18495908-18495908","Variation":"rs75347775","attributes":{"risk_allele":"A","external_reference":"PMID:31046077","associated_gene":"GDF15","beta_coefficient":"0.0097 unit increase","p_value":"1.00e-8"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs3809297","attributes":{"external_reference":"PMID:32722627","risk_allele":"T","odds_ratio":"1.326","p_value":"5.00e-7"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"12:111609727-111609727"},{"attributes":{"associated_gene":"AHR","beta_coefficient":"0.0387 unit increase","p_value":"4.00e-142","risk_allele":"C","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","Variation":"rs4410790","location":"7:17284577-17284577","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"location":"10:69886950-69886950","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"associated_gene":"MYPN","beta_coefficient":"0.0083 unit increase","p_value":"3.00e-8","risk_allele":"C","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","Variation":"rs10997940"},{"location":"16:70927078-70927078","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:32193382","risk_allele":"C","p_value":"6.00e-10","beta_coefficient":"0.0140255 unit decrease"},"Variation":"rs8056750"},{"location":"12:112930475-112930475","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"odds_ratio":"1.293","risk_allele":"C","external_reference":"PMID:32722627","p_value":"5.00e-6"},"mapped_to_accession":"EFO:0004330","Variation":"rs11066325"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"2.00e-6","beta_coefficient":"0.0081 unit increase","associated_gene":"UMAD1"},"Variation":"rs7801593","location":"7:7904397-7904397","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:17287106-17287106","Variation":"rs6968554","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.2 unit decrease","associated_gene":"AHR","p_value":"7.00e-15","risk_allele":"A","external_reference":"PMID:25288136"}},{"Variation":"rs7800944","attributes":{"p_value":"3.00e-11","associated_gene":"MLXIPL,TBL2,VPS37D","beta_coefficient":"0.05 unit decrease","external_reference":"PMID:25288136","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"7:73035857-73035857"},{"attributes":{"p_value":"3.00e-6","beta_coefficient":"0.05616214 unit decrease","associated_gene":"ADORA2A","external_reference":"PMID:31217584"},"mapped_to_accession":"EFO:0004330","Variation":"rs62234058","location":"22:24874523-24874523","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"},{"attributes":{"p_value":"7.00e-12","associated_gene":"LOC102723661","beta_coefficient":"0.0116 unit increase","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","Variation":"rs10127720","location":"1:96273989-96273989","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"location":"7:70053106-70053106","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.0096 unit increase","associated_gene":"AUTS2","p_value":"6.00e-7","risk_allele":"G","external_reference":"PMID:31046077"},"Variation":"rs38319"},{"Variation":"rs13378244","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"2.00e-6","beta_coefficient":"0.0071 unit increase","associated_gene":"LINC00548"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"13:40806355-40806355"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"5:7379003-7379003","Variation":"rs993885","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"G","p_value":"2.00e-9","associated_gene":"ADCY2","beta_coefficient":"0.0092 unit increase"}},{"location":"7:17287106-17287106","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"p_value":"5.00e-13","beta_coefficient":"0.0281684 unit increase","external_reference":"PMID:31217584"},"mapped_to_accession":"EFO:0004330","Variation":"rs6968554"},{"location":"7:75616105-75616105","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","attributes":{"beta_coefficient":"0.07 unit increase","associated_gene":"POR,SNORA14A,TMEM120A","p_value":"4.00e-11","risk_allele":"A","external_reference":"PMID:25288136"},"mapped_to_accession":"EFO:0004330","Variation":"rs17685"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"11:112909396-112909396","Variation":"rs7947502","attributes":{"external_reference":"PMID:31046077","risk_allele":"C","p_value":"6.00e-7","beta_coefficient":"0.0075 unit increase","associated_gene":"NCAM1"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs662799","attributes":{"external_reference":"PMID:31959922","associated_gene":"APOE5","beta_coefficient":"0.066 unit increase","p_value":"4.00e-8"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"11:116663707-116663707"},{"attributes":{"p_value":"6.00e-7","associated_gene":"BDNF","beta_coefficient":"0.04 unit increase","external_reference":"PMID:25288136","risk_allele":"A"},"mapped_to_accession":"EFO:0004330","Variation":"rs12288512","location":"11:27747671-27747671","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:25288136","risk_allele":"A","p_value":"1.00e-9","beta_coefficient":"0.08 unit increase","associated_gene":"POR,SNORA14A,TMEM120A"},"Variation":"rs17685","location":"7:75616105-75616105","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"15:91437388-91437388","Variation":"rs2521501","attributes":{"p_value":"4.00e-8","beta_coefficient":"0.0087 unit increase","associated_gene":"FES","external_reference":"PMID:31046077","risk_allele":"A"},"mapped_to_accession":"EFO:0004330"},{"location":"7:17284989-17284989","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31217584","p_value":"2.00e-10","beta_coefficient":"0.02923515 unit decrease"},"Variation":"rs10277582"},{"location":"HSCHR6_MHC_DBB:31857898-31857898","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","attributes":{"p_value":"7.00e-10","associated_gene":"C2","beta_coefficient":"0.0095 unit increase","external_reference":"PMID:31046077","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","Variation":"rs586346"},{"Variation":"rs11066015","attributes":{"p_value":"8.00e-6","risk_allele":"A","odds_ratio":"1.28","external_reference":"PMID:32722627"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"12:112168009-112168009"},{"Variation":"rs2216084","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:27561104","beta_coefficient":"0.082 unit increase","associated_gene":"Intergenic","p_value":"9.00e-9"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"6:107553312-107553312"},{"Variation":"rs4128436","attributes":{"p_value":"2.00e-8","beta_coefficient":"0.06 NR cups per day decrease","associated_gene":"CLK3,EDC3","external_reference":"PMID:31837886","risk_allele":"T"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"15:74935894-74935894"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"6:107562914-107562914","Variation":"rs9386630","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:27561104","associated_gene":"Intergenic","beta_coefficient":"0.082 unit increase","p_value":"1.00e-8"}},{"location":"7:91863700-91863700","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","attributes":{"p_value":"1.00e-7","beta_coefficient":"0.0078 unit increase","associated_gene":"KRIT1","external_reference":"PMID:31046077","risk_allele":"C"},"mapped_to_accession":"EFO:0004330","Variation":"rs2027950"},{"attributes":{"associated_gene":"EHBP1","beta_coefficient":"0.0155 unit increase","p_value":"2.00e-6","risk_allele":"C","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","Variation":"rs115109216","location":"2:62930203-62930203","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:17284577-17284577","Variation":"rs4410790","attributes":{"external_reference":"PMID:31959922","p_value":"8.00e-68","associated_gene":"AGR3,AHR","beta_coefficient":"0.213 unit increase"},"mapped_to_accession":"EFO:0004330"},{"Variation":"rs12201974","attributes":{"associated_gene":"NHEG1","beta_coefficient":"0.0086 unit increase","p_value":"4.00e-6","risk_allele":"T","external_reference":"PMID:31046077"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"6:137275884-137275884"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"HSCHR6_MHC_MCF:32712468-32712468","Variation":"rs9275576","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"6.00e-9","associated_gene":"HLA-DQA2","beta_coefficient":"0.048 NR cups per day increase","external_reference":"PMID:31837886","risk_allele":"T"}},{"Variation":"rs58806801","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31959922","associated_gene":"CYP1A2,CSK","beta_coefficient":"0.084 unit decrease","p_value":"2.00e-9"},"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"15:75059546-75059546"},{"Variation":"rs6968865","attributes":{"associated_gene":"AHR","beta_coefficient":"0.26 cups per day increase","p_value":"2.00e-11","risk_allele":"T","external_reference":"PMID:21357676"},"mapped_to_accession":"EFO:0004330","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"7:17287269-17287269"},{"location":"HG1257_PATCH:73088583-73088583","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"risk_allele":"G","external_reference":"PMID:31046077","beta_coefficient":"0.019 unit increase","associated_gene":"MLXIPL","p_value":"2.00e-18"},"Variation":"rs34060476"},{"Variation":"rs34060476","mapped_to_accession":"EFO:0004330","attributes":{"beta_coefficient":"0.0309338 unit decrease","p_value":"2.00e-23","risk_allele":"A","external_reference":"PMID:32193382"},"description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog","location":"HG1257_PATCH:73088583-73088583"},{"attributes":{"p_value":"3.00e-7","external_reference":"PMID:32722627","risk_allele":"C","odds_ratio":"1.33"},"mapped_to_accession":"EFO:0004330","Variation":"rs3782886","location":"12:112110489-112110489","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"6:31837277-31837277","Variation":"rs660550","attributes":{"associated_gene":"SLC44A4","beta_coefficient":"0.034 NR cups per day decrease","p_value":"8.00e-9","risk_allele":"A","external_reference":"PMID:31837886"},"mapped_to_accession":"EFO:0004330"},{"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"4:23935053-23935053","Variation":"rs4697428","mapped_to_accession":"EFO:0004330","attributes":{"p_value":"3.00e-6","associated_gene":"PPARGC1A","beta_coefficient":"0.012 unit increase","external_reference":"PMID:31046077","risk_allele":"T"}},{"Variation":"rs10252701","attributes":{"risk_allele":"C","external_reference":"PMID:31345160","beta_coefficient":"0.171 unit decrease","associated_gene":"AHR","p_value":"1.00e-14"},"mapped_to_accession":"EFO:0004330","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption","location":"7:17280513-17280513"},{"mapped_to_accession":"EFO:0004330","attributes":{"associated_gene":"SPECC1L-ADORA2A","beta_coefficient":"0.0442 unit increase","p_value":"2.00e-12","risk_allele":"G","external_reference":"PMID:31046077"},"Variation":"rs2330783","location":"22:24747031-24747031","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog"},{"Variation":"rs2472297","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:21357676","risk_allele":"T","p_value":"5.00e-14","associated_gene":"CYP1A1,CYP1A2","beta_coefficient":"0.31 cups per day increase"},"description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","location":"15:75027880-75027880"},{"source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)","location":"22:24874523-24874523","Variation":"rs62234058","attributes":{"associated_gene":"ADORA2A","beta_coefficient":"0.04113796 unit decrease","p_value":"4.00e-7","external_reference":"PMID:31217584"},"mapped_to_accession":"EFO:0004330"},{"mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:32193382","risk_allele":"C","p_value":"5.00e-36","beta_coefficient":"0.0290606 unit decrease"},"Variation":"rs1057868","location":"7:75615006-75615006","source":"NHGRI-EBI GWAS catalog","description":"Coffee consumption (cups per day)"},{"location":"4:106082120-106082120","description":"Coffee consumption","source":"NHGRI-EBI GWAS catalog","mapped_to_accession":"EFO:0004330","attributes":{"external_reference":"PMID:31046077","risk_allele":"A","p_value":"2.00e-7","beta_coefficient":"0.0079 unit increase","associated_gene":"TET2"},"Variation":"rs13123752"},{"attributes":{"beta_coefficient":"0.0146071 unit increase","p_value":"5.00e-11","risk_allele":"G","external_reference":"PMID:32193382"},"mapped_to_accession":"EFO:0004330","Variation":"rs12514566","location":"5:7391462-7391462","description":"Coffee consumption (cups per day)","source":"NHGRI-EBI GWAS catalog"}]