{"definition":"A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.","namespace":"cellular_component","accession":"GO:0005667","subsets":["goslim_pir"],"name":"transcription regulator complex","children":[{"definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.","namespace":"cellular_component","name":"RNA polymerase II transcription regulator complex","accession":"GO:0090575","subsets":[],"ontology":"GO","synonyms":["RNA polymerase II transcription factor complex"]},{"ontology":"GO","subsets":["goslim_pir"],"synonyms":["transcription factor inhibitor complex","transcriptional repressor complex","cytoplasmic transcriptional repressor complex","nuclear transcriptional repressor complex"],"definition":"A protein complex that possesses activity that prevents or downregulates transcription.","namespace":"cellular_component","accession":"GO:0017053","name":"transcription repressor complex"},{"subsets":[],"ontology":"GO","synonyms":["RNA polymerase III transcription factor complex"],"definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.","namespace":"cellular_component","name":"RNA polymerase III transcription regulator complex","accession":"GO:0090576"},{"name":"NuRD complex","accession":"GO:0016581","namespace":"cellular_component","definition":"An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.","synonyms":["NRD complex","nucleosome remodeling and histone deacetylation complex","Mi-2 complex"],"subsets":[],"ontology":"GO"},{"subsets":[],"ontology":"GO","synonyms":["SNAPc"],"definition":"A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.","namespace":"cellular_component","accession":"GO:0019185","name":"snRNA-activating protein complex"},{"synonyms":["RNA polymerase I transcription factor complex"],"subsets":[],"ontology":"GO","name":"RNA polymerase I transcription regulator complex","accession":"GO:0000120","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.","namespace":"cellular_component"},{"definition":"A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.","namespace":"cellular_component","accession":"GO:1990622","name":"CHOP-ATF3 complex","ontology":"GO","subsets":[],"synonyms":["ATF3-CHOP complex","CHOP-ATF3 heterodimer","CHOP-ATF3 heterodimeric complex","GADD153-ATF3 complex"]},{"synonyms":["RNA polymerase IV transcription factor complex"],"ontology":"GO","subsets":[],"accession":"GO:0090577","name":"RNA polymerase IV transcription regulator complex","namespace":"cellular_component","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV."},{"synonyms":["RNA polymerase V transcription factor complex"],"subsets":[],"ontology":"GO","accession":"GO:0090578","name":"RNA polymerase V transcription regulator complex","definition":"A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.","namespace":"cellular_component"},{"ontology":"GO","subsets":[],"synonyms":[],"definition":"A protein complex which is capable of sigma factor antagonist activity.","namespace":"cellular_component","name":"sigma factor antagonist complex","accession":"GO:1903865"},{"synonyms":["ModE dimer"],"subsets":[],"ontology":"GO","accession":"GO:1990198","name":"ModE complex","definition":"A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.","namespace":"cellular_component"},{"namespace":"cellular_component","definition":"A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.","accession":"GO:0089713","name":"Cbf1-Met4-Met28 complex","subsets":[],"ontology":"GO","synonyms":[]}],"parents":[{"synonyms":["macromolecular complex","macromolecule complex","protein containing complex","protein complex","protein-protein complex"],"ontology":"GO","subsets":["goslim_agr","goslim_chembl","goslim_euk_cellular_processes_ribbon","goslim_flybase_ribbon","goslim_mouse","goslim_pir"],"name":"protein-containing complex","accession":"GO:0032991","namespace":"cellular_component","definition":"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together."}],"ontology":"GO","synonyms":["cytoplasmic transcription factor complex","nuclear transcription factor complex","transcription factor complex"]}